The overall infection rate of HP in the tested population is 30%, including 32.7% for adults and 11.4% for children … Recently, Jiangsu released the "Helicobacter pylori infection and drug resistance map" for the first time.

The infection map shows that the infection rates in Changzhou, Zhenjiang, Taizhou, Xuzhou, Suzhou, Nantong, Nanjing and Yangzhou are all higher than the overall infection rate in Jiangsu Province, with Changzhou being the highest, accounting for 42.9%. The infection rates of 13 prefecture-level cities are shown in the following figure:

2023 Edition of Helicobacter Pylori Infection Map in Jiangsu Province

Helicobacter pylori will live in the epithelium of gastric mucosa, and the urease it secretes can affect the secretion of gastric acid and destroy the barrier of gastric mucosa, which is also one of the important causes of chronic gastric disease, gastric or duodenal ulcer and even gastric cancer. The number of people infected with Helicobacter pylori in China is very high. In recent years, with the promotion of health science popularization, people’s understanding of Helicobacter pylori has gradually deepened.

What is Helicobacter pylori?

Helicobacter pylori is a kind of bacteria. After entering the human body from the oral cavity, it is fixed in the stomach, which can cause a variety of diseases in and out of the stomach. After fixed, it is difficult for the body to remove it spontaneously, resulting in lasting or lifelong infection. In 1994, Helicobacter pylori was listed as a class I carcinogen of human gastric cancer by the World Health Organization (WHO) and the International Agency for Research on Cancer (IARC). In 2022, the United States Department of Health and Human Services listed Helicobacter pylori as a clear carcinogen.

Helicobacter pylori infection is the main risk factor of gastric cancer, which can significantly increase the risk of gastric cancer (3-6 times), and eradication of Helicobacter pylori can reduce the risk of gastric cancer by 54%, which plays a clear etiological role.

How about infectivity?

Helicobacter pylori infection is an infectious disease that can spread from person to person, especially among family members.

Helicobacter pylori infection is a global problem, and the global infection rate has exceeded 50%. A recent screening result shows that the personal infection rate in China is about 40%, and the family infection rate is about 70%. The infection rate increases with age.

People are generally susceptible to Helicobacter pylori. Including people with low education, high family density, low income, eating out more and poor hygiene habits.

It has been pointed out that children are susceptible to Helicobacter pylori, and the infection within the family mainly occurs before the age of 12. Both parents were infected with Helicobacter pylori, and the infection rate of their children was 69.34%. This also suggests that adults in families with children should pay special attention to the detection of HP, find that infection should be actively eradicated, pay attention to not sharing tableware in life, and do not chew and feed infants to avoid HP infection in the family.

75% of adult infected people carry "virulent strains"

In the whole province, 75.6% of HP strains were infected by adults, and 60.5% were infected by children.

Helicobacter pylori strains with certain virulence factors can help them colonize human stomach and survive for a long time, and even induce intestinal differentiation and intestinal metaplasia, leading to the irreversible stage of cancer. There are a large number of virulent strains in the province, which should be paid more attention to. After personal infection, we should cooperate with doctors to actively carry out eradication treatment.

What are the symptoms after infection?

Helicobacter pylori infection sometimes has no obvious symptoms. Symptoms can be manifested as bad breath, belching, loss of appetite, fullness, discomfort in the upper and middle abdomen, dull pain, and even symptoms of acid reflux, nausea and vomiting.

What diseases are they related to?

In the digestive system, Helicobacter pylori infection is an important pathogenic factor of chronic active gastritis, peptic ulcer, gastric mucosa-associated lymphoid tissue (MALT) lymphoma and gastric cancer. Especially in patients with peptic ulcer, the infection rate of Helicobacter pylori is extremely high. Eradication of Helicobacter pylori can promote ulcer healing and significantly reduce the recurrence rate of ulcer.

In addition, Helicobacter pylori is also related to some non-digestive diseases. Helicobacter pylori infection in the blood system is related to unexplained iron deficiency anemia, primary immune thrombocytopenia, vitamin B12 deficiency and other diseases. For patients with these diseases, Helicobacter pylori should be detected and eradicated. With regard to the manifestations of nervous system, more and more studies have linked this bacterium with multiple sclerosis, Alzheimer’s disease, Parkinson’s disease and Guillain-Barre syndrome. Interestingly, the risk of cardiovascular diseases such as atherosclerosis is also affected by infection.

How to prevent it every day?

Helicobacter pylori is particularly prone to family cluster infection, so it is necessary to mobilize the whole family to prevent it and treat it at the same time if necessary. Disinfection of bowls and chopsticks, sharing meals, paying attention to oral hygiene, changing toothbrushes regularly and exercising more to enhance immunity are the most critical measures to prevent this bacterial infection. If the tableware is recycled and not disinfected in time, it may also infect Helicobacter pylori. In addition, parents and children’s tableware should be used separately, and the habit of feeding infants or giving chewed food to children should be abandoned. Patients after radical treatment should also pay attention to prevent reinfection, mainly to prevent reinfection through daily intimate contact.

Which groups of people suggest checking?

First of all, people and their families who have been confirmed to have stomach diseases such as gastric ulcer, chronic gastritis and gastric cancer; Secondly, people who feel abdominal distension, abdominal pain, nausea and other digestive tract discomfort symptoms; The latest research recommends that the family members of patients with Helicobacter pylori positive should also be tested for Helicobacter pylori.

The two antibiotics are highly resistant.

According to experts, we usually talk about the drug resistance of Helicobacter pylori, which tests the sensitivity of the strains carried by infected people to antibiotics.

Jiangsu "drug resistance map" shows that the resistance rate of adults and children to clarithromycin is over 50%, of which the resistance rate of adults to clarithromycin is 51.9% and that of children to clarithromycin is 55.8%. This result is obviously higher than the drug resistance reported in the current literature. According to "Systematic Review and Meta-analysis of Primary Antibiotic Resistance of Helicobacter pylori in China", the drug resistance rate of clarithromycin reached 34% from 2016 to 2020.

Jiangsu "drug resistance map" also shows that the drug resistance rate of adults to levofloxacin is nearly 40%, and that of children to levofloxacin is 23.3%. The resistance rate of adults to furazolidone is 10%, and that of children is 4.7%. The two populations were basically not resistant to amoxicillin and tetracycline.

2023 Edition of the "Drug Resistance Map" of Helicobacter pylori in Jiangsu Province

According to the "Urban Drug Resistance Map" released by Jiangsu Province, the drug resistance of Helicobacter pylori in 13 districts and cities in Jiangsu Province is different.

Huai ‘an City has the highest drug resistance rate of levofloxacin among 13 districts and cities, with a drug resistance rate of 66.7%. The resistance rate of clarithromycin in Yangzhou was the highest, accounting for 69.6%. Yancheng is the city with the highest drug resistance rates of amoxicillin and furazolidone, which are 2.3% and 20.9% respectively.

The difference of drug resistance in different cities suggests that each region or even everyone is infected with different strains of Helicobacter pylori, and there are also differences in individual medication history and local medication habits. Therefore, when HP infected people receive eradication treatment, if they can obtain the individual drug resistance of Helicobacter pylori, choose sensitive antibiotics and avoid antibiotics with known drug resistance, theoretically, the success rate of the first eradication can be greatly improved.

Professor Wang Qizhi, chairman of the Gastroenterology Branch of Anhui Medical Association, pointed out that it is very important to know the antibiotic resistance in the eradication of Helicobacter pylori. The drug resistance and corresponding treatment are different in different regions. With empirical treatment, the eradication effect will be different. Drug resistance is also the main obstacle to the prevention and control of this disease.

Which groups of people suggest eradication? What about the treatment plan?

Family members infected with Helicobacter pylori are always potential sources of infection and have the possibility of continuous transmission to other family members, but whether they are infected or not is related to the intimacy of contact and genetic background. All adults infected with Helicobacter pylori in the family should consider eradication treatment. Especially those who are over 35 years old, have a family history of gastric cancer and a history of gastropathy. According to the risk assessment, children with peptic ulcer and gastric MALT lymphoma can consider eradication treatment, and children with chronic gastritis, family history of gastric cancer, unexplained refractory iron deficiency anemia, long-term NSAID (including low-dose aspirin), guardians or elderly children (12-14 years old) who strongly demand treatment can also consider eradication. For the elderly people infected with Helicobacter pylori in the family, they often suffer from a variety of other systemic diseases at the same time, and the combined medication is complicated. Therefore, before eradication treatment, we should evaluate the risks and benefits and choose an individualized and standardized treatment plan. At present, the commonly used treatment for eradicating Helicobacter pylori in China is bismuth-containing quadruple therapy, that is, a proton pump inhibitor (PPI)+ bismuth+two antibiotics. Because Helicobacter pylori is easily resistant to antibiotics, it is very important to choose the first treatment plan. It is suggested that you must go to the gastroenterology department of a regular hospital for treatment. After the eradication of Helicobacter pylori, C13 and C14 breath tests were performed again one month after drug withdrawal to evaluate the curative effect, and gastroscopy should be performed if necessary.

　　Xinhua News Agency, Tianjin, November 24th (Reporter Yin Siyuan, Zhang Jianxin) There are high incidence of respiratory infections in winter, and some children have typical symptoms of respiratory infections such as fever, sore throat and cough. Monitoring data show that mycoplasma pneumoniae infection and influenza virus infection are the main types of patients currently in hospital. How to distinguish mycoplasma pneumoniae infection from influenza virus infection? Is self-medication feasible? Under what circumstances do you need to see a doctor? The reporter interviewed relevant experts to answer questions.

　　Li Yuechuan, director of the Department of Respiratory and Critical Care Medicine of Tianjin Chest Hospital, said that mycoplasma is a pathogenic microorganism, smaller than bacteria and larger than viruses. Mycoplasma pneumoniae is one of the subtypes, which mainly invades the respiratory system and then causes infection, accompanied by fever, cough and other symptoms. How to distinguish mycoplasma pneumoniae infection from influenza? Li Yuechuan said that in terms of symptoms, the fever caused by mycoplasma pneumoniae infection is generally more than 38 C. If there is a high fever above 39 C, it is highly likely to be influenza A; In terms of headache symptoms, the headache caused by mycoplasma infection is often severe, and the severe headache caused by influenza A is less; Cough symptoms caused by mycoplasma and influenza virus are also different. Cough caused by influenza A is generally not severe, while mycoplasma pneumoniae infection is more likely to cause severe cough symptoms. In addition, mycoplasma infection may also cause rash, meningitis, hemolysis and other symptoms in children.

　　After the child has symptoms such as fever and cough, some parents choose to give their children azithromycin and other drugs. In view of this phenomenon, Xu Yongsheng, director and chief physician of the Respiratory Department of Tianjin Children’s Hospital, said that azithromycin has a good effect on the treatment of mycoplasma pneumoniae infection, but it is not necessarily the best choice for other pathogens. "The use of azithromycin depends on age and basic state, and not all children can use it. Therefore, it is not advisable to take antibacterial drugs blindly. " Xu Yongsheng said.

　　On November 22nd, in Tianjin Children’s Hospital, many parents brought their children to see a doctor. (Photo courtesy of the interviewee)

　　Under what circumstances does the child need to go to the hospital? Xu Yongsheng said that for most children, respiratory tract infection is self-limited, and the symptoms are often the external manifestations of the body’s struggle with pathogens. With more rest and more water, most children can overcome pathogens. However, if the following situations occur, it is necessary to seek medical attention in time: First, the condition of children in the younger group changes rapidly and the symptoms are atypical, so parents often find it difficult to identify critical situations and need to seek medical attention as soon as possible; Second, it is necessary to assess the child’s mental state. If there are symptoms such as listlessness, less communication and interaction, and indifference, you need to go to the hospital in time; Third, when the symptoms are not relieved after a long course of disease, you need to go to the hospital for further diagnosis and treatment.

　　How should students guard against it? Dong Xiaochun, chief physician of the Center for Infectious Diseases Prevention and Control of Tianjin Center for Disease Control and Prevention, said that students should develop good personal hygiene habits, cover their nose and mouth when coughing or sneezing, and pay attention to hand hygiene; Report to teachers and parents immediately when you feel unwell, so as to avoid attending classes with illness; Wear a mask when going out to reduce activities in crowded places; When parents find that their children have fever, cough and other related symptoms, they should seek medical treatment in time.

CCTV News:With regard to the operation of China’s economy, many international financial institutions said that in the first quarter of this year, China’s macroeconomic development showed many bright spots, including the rebound in consumption, steady investment in service industry and infrastructure, and foreign trade growth exceeding expectations. Among them, the wholly-owned company established by Fitch Ratings in China — — Tang Daqian, an analyst at Fitch Bohua, pointed out that consumption plays a significant role in boosting China’s economy.

Tang Daqian, Deputy Director of Huiyu Bohua Industrial and Commercial Enterprise Department:With the expansion of consumption radius and richer consumption scenarios, this directly beneficial service industry may recover more vigorously. We are optimistic about China’s economic growth in the first quarter of 2023, including the whole year. We believe that China’s economic growth is resilient.

Looking forward to the whole year of 2023, analysts predict that China’s economic growth will continue to maintain a "steady to good" trend in the future and lead the world.

Xing Ziqiang, Chief Economist of Morgan Stanley China:We judge that after a strong recovery in the first quarter, China’s economic growth (speed) is expected to reach 5.7% this year, contributing more than 40% to the global economic growth, and China and Asia have outperformed and led the world.

　　In order to promote consumption and promote the popularization of green and energy-saving household appliances, Jiangsu Province has implemented a series of state subsidy policies. These policies not only cover traditional household appliances, but also extend to 3C digital products such as smart phones. This paper will introduce in detail the operation process of Jiangsu’s national subsidy policy in 2024, especially how to receive mobile phone subsidies to help consumers better understand and enjoy this preferential policy.

　　First, the operation process of Jiangsu state subsidy policy in 2024

　　1. Scope and standard of subsidies

　　Jiangsu’s state subsidy policy mainly aims at qualified individual consumers, and provides financial subsidies when purchasing designated household appliances and 3C digital products. The subsidy is applicable from September 7, 2024 to December 31, 2024. The household appliances covered by the policy include eight traditional categories (such as televisions, refrigerators, washing machines, etc.), as well as a variety of additional household appliances and smart household appliances (projectors) in Jiangsu Province. In addition, 3C digital products, such as mobile phones, tablet computers, wireless Bluetooth headsets, etc., are specially included.

　　2. Operation process of state subsidy policy

　　Note that Jiangsu household appliances subsidies do not need to be specially collected (but the receiving address is only available in Jiangsu Province). Select the appliances you want to buy (participate in household appliances subsidies) and the order will be fully reduced automatically.

　　Step one:Download and register CCB Life APP.

　　Consumers first need to download the "CCB Life" APP in the app store and complete the registration. During the registration process, you need to enter the mobile phone verification code, set the password, and carry out real-name authentication. After real-name authentication, open the wallet and bind the bank card to support debit cards or credit cards of major banks.

　　Step two:Open JD.COM APP and enter "projector state subsidy" in the search bar to enter the "Digital State subsidy page". This page lists all regions participating in the national subsidy policy. Taking Jiangsu Province as an example, users can click "Jiangsu Province" to enter the corresponding area;

　　Step two:Then click the link "Click into the Zone without qualification" on the page, and select "Projector" from the classification;

　　Step 3:Users can choose their favorite projector model and enter the product details page. There will be a logo of "State Subsidy" on the page. When making purchase and payment, please pay attention to confirm that the receiving address is set to Jiangsu Province and selectChina construction bank life APPPay to enjoy the subsidy policy.

　　Precautions:

　　1. Jiangsu subsidy policy is open to national IP addresses, but the receiving address needs to be in Jiangsu Province;

　　2. Each consumer can only enjoy one subsidy for each product, and the subsidy amount is limited;

　　3. Please carefully check the product information, subsidy policy and return rules before purchasing;

　　4. If you have any questions about the subsidy collection, you can consult the customer service of Dangbei Store;

　　5. The national subsidy policy may change in real time, so it is recommended to get early and enjoy preferential treatment.

　　Second, Jiangsu Guobu mobile phone subsidy process

　　Step 1: Confirm the subsidy qualification.

　　Through the "CCB Life" APP, enter the "Suxin Consumption Green Energy-saving Home Appliances Trade-in Special Activity" area. Customers who participate in the activity for the first time need to complete the real-name authentication and register first. After successful registration, they can apply for the eight categories of household appliances subsidies designated by the state with one click on the activity page. For the increased household appliances and 3C digital products in Jiangsu Province, there is no need to apply for subsidy qualification separately.

　　Step 2: Buy subsidized products.

　　After the application for subsidy qualification is completed, consumers can go to offline stores or online sales enterprises participating in the activities to purchase goods within the scope of subsidies. For 3C digital products such as mobile phones, consumers can find and select the style they want to buy on the APP and confirm the subsidy amount.

　　Step 3: Complete the payment

　　After the purchase is completed, consumers can complete the payment in stores or online platforms. When paying offline, the store staff will confirm the subsidy qualification and place an order in advance, and the consumer will check the order to be paid in the APP and complete the payment. When making online payment, the consumer clicks "Su Xin Consumption-CCB Life" when placing an order for payment, guiding to jump to the APP to complete the payment, and returning to the online sales enterprise to confirm the payment result.

　　Step 4: Pay and enjoy the subsidy.

　　In the payment process, the system will automatically calculate the subsidy amount, and consumers only need to pay the amount after deducting the subsidy. After the payment is successful, consumers can choose to pick it up at the store or deliver it home.

　　Precautions:

　　For 3C digital products, the subsidy is also based on 15% of the discounted price of the enterprise, and each person is limited to one product of each type, with the subsidy ceiling of 1,500 yuan. 3C digital product subsidies are limited to offline stores.When buying mobile phones, tablets and other electronic products that are easy to realize, it is necessary to unpack and activate them on site.Stores should keep clear activation photos including SN code, IMEI code, package SN code, shopping receipt or personal ordinary invoice (indicating the machine model) and activation date to ensure that all information is consistent.

　　Third, the new area collection process:

　　1.2024 government home appliance subsidy projector inventory! Zhejiang/Guangdong/Fujian/Sichuan and many other places can get it.

　　2. How to use government subsidies for trade-in in Hubei? Hubei trade-in subsidy collection method

　　3.2024 How to get the old-for-new subsidy in Guangdong? Guangdong Trade-in Subsidy Collection Course

　　4. How does Zhejiang Province use home appliance subsidies to purchase projection? Tutorial for Replenishment of Dangbei Projection Country in 2024

　　5. How does Dangbei Projection in Sichuan Province receive the government renewal subsidy? Detailed course of actual measurement

This article is transferred from "Xin Zhixun"

On September 19th this year, Huawei officially released the annual flagship Mate 30 and Mate 30 Pro in Munich, Germany, and also announced the 5G version of Mate 30 series equipped with Kirin 990 5G chip. However, it was not until November 1st, more than a month after the launch of the 4G version of Mate30 series, that the 5G version of Huawei Mate 30 series, which was priced at 4999 yuan, was finally put on sale, and the sales in Huawei’s official mall exceeded 700 million in seven minutes.

Recently, TechInsights, a foreign professional analysis organization, conducted an in-depth disassembly analysis of Mate30 Pro 5G version (version of 8GB RAM+256GB ROM), which not only analyzed the main components on the motherboard of Mate30 Pro 5G version, but also included the disassembly analysis of Kirin 990 5G processor.

Let’s take a look at it:

According to TechInsights’ analysis of the motherboard of Mate30 Pro 5G,

Look at the front of the motherboard first. As indicated in the above figure, the components from left to right are:

Haisi Hi6421 power management IC

Haisi Hi6422 power management IC

Haisi Hi6422 power management IC

Haisi Hi6422 power management IC

Nxp PN80T secure NFC module

STMicroelectronics (stmicroelectronics) BWL68 Wireless Charging Receiver IC

Halo Micro (Guangdong Xidi Microelectronics) HL1506 Battery Management IC

Look at the back of the motherboard first. As indicated in the above figure, the components from left to right are:

Halo Micro (Guangdong Xidi Microelectronics) HL1506 Battery Management IC

Haisi Hi6405 audio codec

STMP03 (unknown)

Silicon Mitus SM3010 power management IC (possible)

Cirrus Logic CS35L36A audio amplifier

Lianfa technology MT6303 envelope tracker IC

Haisi Hi656211 power management IC

Haisi Hi6H11 LNA/RF switch

Murata front-end module

Haisi Hi6D22 front-end module

HiSilicon Kirin 990 5G SoC and SK Hynix H9HKNNNFBMAU-DRNEH 8GB Mobile LPDDR4X SDRAM with PoP package.

Samsung KLUEG8UHDB-C2D1 256GB UFS storage

Texas Instruments TS5MP646 MIPI switch

Texas Instruments TS5MP646 MIPI switch

Haisi Hi1103 Wi-Fi/BT/GNSS wireless integrated IC

Haisi Hi6H12 LNA/RF switch

Haisi Hi6H12 LNA/RF switch

Cirrus Logic CS35L36A audio amplifier

Haisi Hi6D03 MB/HB power amplifier module

After introducing the motherboard, let’s take a look at another sub-version:

As indicated in the above figure, from left to right are:

Haisi Hi6365 RF transceiver

Unknown 429 power amplifier (possible)

Haisi Hi6H12 LNA/RF switch

Qualcomm QDM2305 front-end module

Haisi Hi6H11 LNA/RF switch

Haisi Hi6H12 LNA/RF switch

Haisi Hi6D05 Power Amplifier Module

Murata front-end module

Unknown 429 power amplifier (possible)

Let’s take a look at the internal situation of Kirin 990 5G:

As mentioned before, Kirin 990 5G integrated Huawei’s Ba Long 5005G baseband chip into the SoC for the first time, which made it the world’s first commercial 5G SoC, and also supported the SA/NSA dual-mode and backwards compatibility 4G/3G/2G network. In contrast, at present, other commercial 5G mobile phones are basically implemented in the form of processor plug-in 5G baseband, which will further increase the cost and power consumption.

Kirin 990 5G adopts PoP package, and SK Hynix H9HKNNNFBMAU-DRNEH 8GB mobile LPDDR4X SDRAM is stacked on top of it, which is the same as what we saw in Huawei Mate 20 X(5G) before.

The chip size of Kirin 990 5G SoC is 10.68mm x 10.61mm = 113.31mm 2. In contrast, the chip size of Mate 20 X(5G) and Kirin 9804G AP+modems is 8.25mm x 9.16mm = 75.57mm2, while the chip size of Balong 5000, an independent 5G modem, is 9.82mm x 8.74mm = 85.83mm2. Kirin 980 4G AP/modem chip size+5G Balong modem chip size = 161.4mm2 The die size of Kirin 990 5G SoC is 113.31mm2, which is much smaller than the previous two-component solution, which may be benefited from TSMC’s latest 7nm FinFET EUV technology.

Comparison of chip sizes between Kirin 980 (left) and Kirin 990 5G (right)

Summary: From the main 36 components in Huawei Mate 30 Pro 5G version listed above, 18 of them are from Huawei HiSilicon’s self-developed chips, accounting for half of the total. Moreover, we can see that Huawei also introduced the battery management chip of Guangdong Xidi Microelectronics, a domestic chip manufacturer, and the envelope tracking chip of MediaTek in flagship machine for the first time. In addition, we can also see that the proportion of components from Japan, South Korea and Europe is also increasing. The front-end module of Murata in Japan, the silicon micro-power management IC in South Korea and the wireless charging chip of Legally Semiconductor in Europe all seem to enter Huawei’s flagship models for the first time.

Surprisingly, among the core components of Huawei Mate 30 Pro 5G version, there are still American devices, such as chips from Texas Instruments, and the RF front-end module of Qualcomm and the audio amplifier of Lingyunluo of the United States have appeared for the first time. At present, the United States has not lifted the ban on Huawei, and these American devices should have been stocked by Huawei before. However, compared with the previous internal main components of Mate 20 X 5G, the proportion of components from the United States is indeed further reduced. For example, instead of Qorvo and Skyworks front-end modules, there are more HiSilicon RF front-end devices and Murata front-end modules, and Meguiar’s DRAM has also been replaced by SKHynix’s.

　　On April 18th, the Information Office of Shanghai Municipal People’s Government held a press conference on epidemic prevention and control to introduce the latest situation.

　　A reporter asked: can you ask experts to introduce how to correctly kill at home and in the office? Everyone has stockpiled some disinfection supplies. How to store them safely? How long is the shelf life of commonly used disinfection products?

　　Tian Liang, chief physician of the Institute of Infectious Diseases Prevention and Control and the Department of Disinfection and Infection Control of Shanghai CDC, responded that we need to follow several principles in carrying out disinfection at home and in the office. First, the principle of cleaning first and disinfection second: under normal circumstances, do a good job in environmental cleaning, and carry out disinfection for links and objects with real risks. Disinfection should be carried out on the premise of completing cleaning. Second, the principle of giving priority to physical methods, supplemented by chemical methods: giving priority to the use of disinfection methods including window ventilation, mechanical ventilation, heating and boiling, and sun exposure. Third, the principle of combining preventive disinfection with disinfection at any time: disinfect all kinds of articles, elevators, handrails, toilets, etc. daily, once or twice a day. In case of pollution, carry out disinfection at any time and clean hands at any time. Fourth, the principle that the disinfection intensity is consistent with the risk level: the disinfection frequency can be higher for articles that are frequently contacted, the disinfection concentration of seriously polluted objects can be appropriately increased, and the disinfection time can be appropriately extended. Fifth, do personal protection during disinfection, not only to prevent pathogen infection, but also to prevent the stimulation and damage of disinfectant to people.

　　There are several common disinfection misunderstandings:

　　First, spray disinfectant on vegetables and fruits — — Usually, the outer packaging of fruits and vegetables can be disinfected, and the fruits and vegetables themselves only need to be cleaned. It is not recommended to use chemical disinfectants for disinfection, so as not to affect food safety and taste. If disinfection is really necessary, you can use disinfectants with fruits and vegetables on file. After soaking for 10-30 minutes according to the concentration in the instructions, rinse with clear water to remove the residual disinfectant.

　　Second, the higher the concentration of disinfectant, the better — — When using disinfectant, make correct configuration according to the concentration of the corresponding object in the instruction. The concentration of disinfectant is not as high as possible, and high concentration disinfectant usually has more side effects such as corrosiveness and irritation, and the workload of removing residues will be greater.

　　Third, spray disinfectant on people and clothes — — Generally speaking, the personal coat is less likely to carry Covid-19; Secondly, when chemical disinfectant is directly sprayed on human body, on the one hand, it will cause irritation and damage to people, and at the same time, because the spraying time is too short and the spraying amount is too small, it can not achieve disinfection effect.

　　Fourth, use humidifiers indoors for "preventive air disinfection" — — On the one hand, the disinfection effect of this method is difficult to guarantee, on the other hand, people are easily hurt by disinfectants, such as respiratory irritation, burns and allergies, which is also a misunderstanding.

　　During the epidemic period, people may have hoarded some disinfection products. When storing disinfectants, they should pay attention to safe storage, sealing and keeping them away from light. Disinfectants should not be placed in bedrooms, kitchens and other places. If there are children at home, children should also be prevented from taking and eating by mistake.

　　The commonly used disinfection products usually has a shelf life of about 2 years before it is opened. After unsealing, it is suggested that alcohol disinfectants should be used up within one month, and other disinfectants should be used up within two months. If it is a diluted disinfectant, it is recommended to use it on the same day.

In 2018, the original animation "Wu Liuqi" produced in Shanghai was born. With its unique style and touching story, it quickly accumulated the first batch of loyal fans. In the second quarter of 2019, "The Strongest Hairstylist of Wu Liuqi" was broadcast, and the popularity and reputation rose again. The animation in the two seasons won the praise of Douban with 8.9 points and 9.2 points. With the announcement of the Magnolia Award in this year’s Shanghai TV Festival, the second season of Wu 67, The Strongest Hairstylist of Wu 67, became the only original animation in China that won the Magnolia Award for Best Animation Script in recent five years.

Award-winning poster of "The Strongest Hairstylist of Wu Liuqi"

"The Strongest Hairstylist of May 67 th combines many elements of online culture, which is casual, simple and fashionable. It is a bold and innovative work with a narrative style." The international judges of this year’s Magnolia Award and well-known animators in the industry all praised the works. John Derderian, head of Netflix Animation, also thinks it is "a high-quality work that has the opportunity to arouse the resonance and favor of animation fans all over the world".

How can an original animated series in China "show the world well" on the basis of retaining its own China characteristics? As a practitioner of China’s cultural and creative industries, Zou Shasha, founder and CEO of Aha Entertainment, producer and producer of Wu Liuqi, shared her feelings.

Zou Shasha

Based on Shanghai, Building a "Talent Platform" for Content Industry

Zou Shasha chose to settle Aha Entertainment in Shanghai before, which is because he took a fancy to the deep animation foundation of this city. China’s first self-made cartoon "Make a scene in the Studio" was brought by Shanghai Wan Brothers, which was released two years earlier than Mickey Mouse of Disney in the United States. Shanghai Animation Film Studio has created a series of excellent original animations of China, which has accompanied the growth of several generations and influenced a large number of animation creators at home and abroad internationally. In recent years, the Shanghai government has also issued many policies, which have greatly supported the animation industry in terms of capital and resources.

"China animation and other story forms need to continue to explore the upgrading in three dimensions: aesthetic presentation, cultural transmission and human thinking, in order to enhance the competitiveness of works in the process of globalization." Zou Shasha introduced that in terms of aesthetic presentation, Wu Liuqi insisted on its own system, "neither American nor Japanese", and explored the aesthetic road with China characteristics. In terms of cultural transmission, "Wu 67" integrates China culture into the plot, with distinct China elements and strong local characteristics, and at the same time, it has international narration. In terms of human thinking, Wu Liuqi takes the protagonist Wu Liuqi’s search for lost memories as the main line of the story, and tells the story that the protagonist uses love and tolerance to resolve hatred and prejudice in the process of helping others and finding himself. "The work takes love and tolerance as the core, and conveys the love for life while bringing joy to the audience. Such a theme can cross national and national boundaries." Zou Shasha said.

Stills of "The Strongest Hairstylist of Wu Liuqi"

In addition to continuously creating high-quality boutique content and building a comprehensive and international content ecology, Aha Entertainment is also committed to discovering and supporting young creators with potential in China. For example, He Xiaofeng, who cast Wu Liuqi, is a very creative director, who not only arranged for the director, screenwriter and camera, but also acted as the voice of the protagonist Wu Liuqi.

Up to now, the "567" animation has been played more than 3 billion times on the whole network, and it has also been shortlisted as the main competition unit of the French Anxi International Animation Film Festival, which is known as the "Oscar in animation". At the beginning of this year, "Wu Liu Qi" even reached a global distribution cooperation with Netflix, and landed in more than 190 countries and regions around the world as the first Netflix Original animated series in China. On May 7th, The Strongest Hairstylist of Wu Liuqi landed on Netflix again, which was the second invitation sent to Wu Liuqi by the world’s top streaming media platform based on its performance, which also meant that Wu Liuqi had told a China story to the world audience, and this story will continue to be told.

Netflix finalized poster of "The Strongest Hairstylist of 567"

Make good use of stories to explore the maximum value of China’s cultural and creative content.

According to statistics, the largest overseas audience of "567" is English-speaking countries, and the total number of fans in the United States and Canada accounts for 35% of the total overseas fans, followed by South America, Europe, and then Japan and Southeast Asia. Netflix itself has always been open to content cooperation in China. In fact, many overseas manufacturers and institutions do not have a particularly obvious understanding of national boundaries and regions, and they are more content-oriented. Zou Shasha said that at present, "donghua" has been used overseas to refer to China animation, just as animation refers to Japanese animation. YouTube also has a well-known kol to comment on China animation in English, which shows that the influence of China animation in overseas markets is gradually rising.

The popularity of "Wu Liu Qi" in Netflix further proves that China, with a history of 5,000 years, has never lacked the source of good stories. However, going to sea is not the ultimate goal, but a way to maximize the value of China’s cultural and creative content. In the future, while improving the level of industrial production and cultivating the long-term vitality of the content, we should also consider the benign interaction between business and content, so that excellent content can have the ability of "automatic hematopoiesis".

Stills of "The Strongest Hairstylist of Wu Liuqi"

In addition to animated series, other IP derivatives such as comics, movies, games, stage plays, publications, live-action film and television dramas, derivatives, music and offline performances are all under planning. The third season of "567" animation is planned to be launched at the end of this year, and then I hope to maintain the rhythm of updating one season every year; At the end of last year, the first comic book "Wu 67: Black and White Ssangyong" based on different protagonists in the world view of Wu 67 was serialized, and there are plans to make it an independent IP in the future; At the same time, four animated cinema films of "Wu Liuqi" have entered the development stage, and the first set of book publications of "Wu Liuqi" will soon be published in more than 3,000 offline bookstores; The "Wu Liu Qi" series hand-made jointly with Bandai Nanmeng Palace in Japan is in hot sale, and there will be more brand-new hand-made launches in the future; Up to now, "567" has reached a linkage authorization with six games, and the linkage version with ByteDance’s popular mobile game "My Kung Fu is awesome" has just been launched.

Netflix launched in the second season of "Wu Liu Qi"

In the past, when talking about IP, people always talked about "Disney Empire" and "Marvel Universe". Zou Shasha hopes that "Wu Liu Qi" can be used as a cultural symbol of China belonging to this era, and accompany audiences of different ages through different IP forms. "The growth space of this’ Shanghai-made’ original animation work is not only in the China market, but also in the future, it will have the opportunity to make the vast global market a consumer market for cultural content and business in China."

Original Sara Novak Neuroreality is included in the topic # Depth | Deep-diving 320 # Cognitive Science 100.

The concept of "clean diet" has a broad definition in the field of health. From strict vegetarianism or fish element * to ketogenic diet or gluten-free diet-we often define ourselves by the kinds of food we eat. Sometimes, whether we give up dairy products or only eat organic food, our strict dietary preferences may turn into some degree of compulsive behavior. As for people suffering from orthorexia, it may become dangerous to be unable to eat any food that they think is unhealthy.

* Translator’s note

It means that all meat is forbidden except fish.

Health food disorder is an eating disorder characterized by refusing to eat anything that is considered "impure" or "unclean". Terri Griffith [2], a clinical coordinator of Shepard Pratt’s Eating Disorder Center, said: "People with healthy food disorders are particularly concerned that they can only have healthy food in their bodies, and they have an unhealthy compulsion for the quality of food." She added that this is a relatively new obstacle, but gradually there has been more and more discussion about it.

– Jeannie Phan –

This concern may also escalate into neurosis. For example, when a person with healthy food syndrome attends a party and there is no food that meets their specific clean eating standards, they may not eat at all. According to Griffith, a clean diet is ok, and this strict standard is the problem. It may start with someone choosing to eat only a certain kind of food, such as a strict vegetarian diet or a low-carbon water diet, but it often develops to exclude the whole food group until the diet becomes too strict.

For people who are more prone to eating disorders, this food exclusion may be an inducement-and the epidemic has made the situation worse. Lauren Smolar, senior director of the American Eating Disorder Association [3] program, explained that patients who are already in the recovery stage may relapse due to various epidemic-related stress factors. In addition, people who could have received treatment may find it difficult to get the help they need because of the blockade, which may make their situation worse and it will be more difficult to recover in the future.

Discussion on diagnosis

Smolar said: "In the end, healthy food disease can lead to serious consequences, including malnutrition and other serious health problems."

For example, this calorie restriction may lead to cardiovascular problems-when the body can’t get enough calories, it begins to break down its own tissues and muscles. And because the heart is a muscle, malnutrition may lead to a weak and slow pulse. Calorie restriction may also lead to gastrointestinal problems and amenorrhea.

Griffith said that patients with healthy food disorders who visit eating disorder centers are usually diagnosed as anorexia)[4] nervosa [4], simply because healthy food disorders are not defined in the Diagnostic and Statistical Manual of Mental Disorders [5] (DSM, which is well known to mental health experts). Although these patients will strictly limit calories, they do not simply limit calorie intake, but adopt critical standards to choose foods that they think are healthy.

– Yuko Furusho –

According to Griffith, it is important to introduce patients to foods outside their comfort zone. She said: "We want to reduce the stigma of’ certain types of food are harmful to them’. We expose them to more diverse foods so that they can become more adaptable to them. "

Smolar added that it is not clear when the health food disease can get its own diagnosis. She said: "There is still disagreement in the literature about whether healthy food disorder is a special eating disorder or related to obsessive-compulsive disorder, so doctors and health experts are still discussing how to advance the next step. “

The nature of this disease makes the diagnosis more difficult to define. Patients not only care about calorie restriction [6], but also want to ensure that their diet consists of certain foods, which is considered by some mental health experts as a feature of obsessive-compulsive disorder. This also makes it difficult for experts to measure the prevalence of health food disease-in different estimates [7], this ratio is as low as less than 7% of the Italian population and as high as nearly 90% of Brazilian students. But Smolar said that this should not affect the way it is treated, and it still needs the professional help of psychologists.

Although health food disease is not a diagnosis, it is clear that the discussion around this obstacle is advancing. It is a cultural trend to pay special attention to what is in the food we eat, but sometimes it may go too far-after all, the pursuit of health will go too far.

references

[1] https://www.discovermagazine.com/health/what-science-says-about-athletes-going-vegan

[2] https://www.sheppardpratt.org/why-sheppard-pratt/our-experts/details/terri-griffith-psyd/

[3] https://www.nationaleatingdisorders.org

[4] https://www.discovermagazine.com/health/a-large-genetic-study-of-anorexia-may-begin-yielding-clues-to-treatment

[5] https://www.psychiatry.org/psychiatrists/practice/dsm

[6] https://www.discovermagazine.com/health/calorie-restricted-diets-may-not-live-up-to-the-hype

[7] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8160773/

Author: Sara Novak | Translator: Meat | Proofreading: Old orange

Editor: Pheasant | Typesetting: Yo Yo Yo | Cover: Daniele Simonelli

Original text:

https://www.discovermagazine.com/health/orthorexia-when-health-consciousness-goes-too-far

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On October 12th, on the occasion of the International Day for the Blind, Fuyang Experimental Primary School in Anhui Province launched an educational activity with the theme of "Experience the life of the blind, and care begins with you and me", and organized students to walk blindfolded with crutches accompanied by teachers, and experience the hardships of the life of the blind in the dark, so as to cultivate children’s awareness of caring for the blind, caring for the blind and actively helping the blind around them. At the same time, it also aims to appeal to the public to consciously give up the blind road and let the blind walk smoothly. China Education News-China Education News Network (photo by correspondent Wang Biao)